Mutational landscape of plasma cell-free DNA identifies molecular features associated with therapeutic response in patients with colon cancer. A pilot study

Abstract Cell-free DNA (cfDNA) has recently been used as a non-invasive diagnostic tool for detecting tumour-specific mutations. cfDNA may also be used for monitoring disease progression and treatment response, but so far researchers focused on one or few genes only. A genomic profile may provide be...

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Bibliographic Details
Published in:	Mutagenesis Vol. 36; no. 5; pp. 358 - 368
Main Authors:	Cervena, Klara, Pardini, Barbara, Urbanova, Marketa, Vodenkova, Sona, Eva, Pazourkova, Veskrnova, Veronika, Levy, Miroslav, Buchler, Tomas, Mokrejs, Martin, Naccarati, Alessio, Vodicka, Pavel, Vymetalkova, Veronika
Format:	Journal Article
Language:	English
Published:	UK Oxford University Press 06-10-2021
Subjects:	Aged Biomarkers, Tumor Cell-Free Nucleic Acids Colonic Neoplasms - blood Colonic Neoplasms - diagnosis Colonic Neoplasms - genetics Colonic Neoplasms - therapy DNA, Neoplasm Female Fluorouracil - pharmacology High-Throughput Nucleotide Sequencing Humans Male Middle Aged Mutation Neoplasm Grading Neoplasm Staging Prognosis Sequence Analysis, DNA
Online Access:	Get full text
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