Tarc, a CC chemokine, is frequently expressed in classic Hodgkin's lymphoma but not in NLP Hodgkin's lymphoma, T-cell-rich B-cell lymphoma, and most cases of anaplastic large cell lymphoma

Thymus and activation-regulated chemokine (TARC) has been identified as a lymphocyte-directed CC chemokine that attracts activated T-helper type 2 (Th2) cells in humans. Recent studies showed that the T cells surrounding Reed-Sternberg cells in Hodgkin's lymphomas (HL) are Th2 type. Anaplastic...

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Bibliographic Details
Published in:	The American journal of surgical pathology Vol. 25; no. 7; pp. 925 - 929
Main Authors:	PEH, S. C, KIM, L. H, POPPEMA, S
Format:	Journal Article
Language:	English
Published:	Hagerstown, MD Lippincott Williams & Wilkins 01-07-2001
Subjects:	Biological and medical sciences Chemokine CCL17 Chemokines, CC - metabolism Diagnosis, Differential Hematologic and hematopoietic diseases Herpesvirus 4, Human - isolation & purification Hodgkin Disease - metabolism Humans Immunohistochemistry Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphoma, B-Cell - metabolism Lymphoma, B-Cell - pathology Lymphoma, B-Cell - virology Lymphoma, Large B-Cell, Diffuse - metabolism Lymphoma, Large B-Cell, Diffuse - pathology Lymphoma, Large B-Cell, Diffuse - virology Medical sciences Reed-Sternberg Cells - metabolism T-Lymphocytes - pathology Human Immunohistochemistry Adult T cell leukemia Hodgkin disease Malignant hemopathy B-Lymphocyte Large cell lymphoma Non Hodgkin lymphoma Lymphoma Differential diagnostic Infection Pathology Lymphoproliferative syndrome Viral disease
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