Effects of Roux-en-Y Gastric Bypass on Resting Energy Expenditure in Women

• Published in: Obesity surgery Vol. 18; no. 11; pp. 1376 - 1380
• Main Authors: de Castro Cesar, Marcelo, de Lima Montebelo, Maria Imaculada, Rasera, Irineu, de Oliveira, Adalberto Vicente, Gomes Gonelli, Pamela Roberta, Aparecida Cardoso, Gabrielle
• Format: Journal Article
• Language: English
• Published: New York Springer-Verlag 01-11-2008; Springer Nature B.V
• Subjects: Adult; Body Mass Index; Calorimetry, Indirect; Energy; Energy Metabolism; Female; Gastrointestinal surgery; Humans; Medicine; Medicine & Public Health; Metabolism; Middle Aged; Obesity; Obesity, Morbid - metabolism; Obesity, Morbid - surgery; Postoperative Period; Research Article; Surgery; Waist-Hip Ratio; Weight control; Weight Loss; Women; Women; Morbid obesity; Indirect calorimetry; Resting energy expenditure; Bariatric surgery; Gastric bypass
• ISSN: 0960-8923; 1708-0428
• DOI: 10.1007/s11695-008-9460-8

Background
Bariatric surgery is the gold standard treatment for morbid obesity, but little is known about its effects on resting energy expenditure.
Method
Twenty-one women underwent anthropometric and resting energy expenditure (REE) measurements before and 3 months after bariatric surgery using the Roux-en-Y gastric bypass (RYGBP) technique developed by Capella.
Results
The patients experienced a significant reduction in body weight, body mass index, waist circumference, and waist-to-hip ratio (WHR). The cardiopulmonary variables oxygen uptake, carbon dioxide output, non-protein respiratory quotient, and heart rate all decreased, whereas oxygen pulse did not change significantly. Absolute REE showed a significant reduction 3 months postoperatively (2006.7 ± 376.4 kcal/day to 1763.3 ± 310.5 kcal/day), but no significant difference was found compared with REE relative to body weight (0.71 ± 0.15 kcal kg
−1
h
−1
to 0.75 ± 0.12 kcal kg
−1
h
−1
) or as percent of Harris-Benedict predicted REE (106.2 ± 21.0% to 103.3 ± 15.1%).
Conclusion
In this study, bariatric surgery using the RYGBP technique (Capella) led to a significant decrease of body weight that decreased resting energy expenditure proportional to this weight loss, and to an increase in the utilization of fat as an energy substrate. It can be concluded that after 3 months, the Roux-en-Y gastric bypass surgery may provide significant metabolic benefits to morbidly obese women.