Importance of In Vitro Embryo Model Procedure Standardization

• Published in: Journal of clinical laboratory analysis Vol. 38; no. 13-14; pp. e25082 - n/a
• Main Authors: Kılıç, Kubilay Doğan, Yılmaz, Zeynep Simge
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01-07-2024; John Wiley and Sons Inc
• Subjects: Cancer; Cooperation; embryo studies; Embryos; Ethics; Genomes; in vitro studies; in vivo studies; Researchers; Standardization; standardized protocols; Stem cells; standardized protocols; in vivo studies; standardization; embryo studies; in vitro studies
• ISSN: 0887-8013; 1098-2825; 1098-2825
• DOI: 10.1002/jcla.25082

ABSTRACT
In vivo studies offer a detailed understanding of organism functioning, surpassing the insights provided by in vitro studies. These experiments are crucial for comprehending disease emergence, progression, and associated mechanisms in humans, as well as for developing treatments. When choosing experimental models, factors such as genomic similarity, physiological relevance, ethical appropriateness, and economic feasibility must be considered. Standardized protocols enhance the reliability, and reproducibility of scientific methods, promoting the assessment of research in the scientific literature. Researchers conducting embryo studies should establish and document standardized protocols for increased data comparability. Standardization is vital for scientific validity, reproducibility, and comparability in both in vivo and in vitro studies, ensuring the accuracy and reliability of experimental results and advancing scientific knowledge.