The role of childhood trauma, HPA axis reactivity and FKBP5 genotype on cognition in healthy individuals

Cognitive impairment has been associated with both childhood adversity and abnormalities of hypothalamic-pituitary-adrenal (HPA) axis function. An interaction exists between the functional polymorphism rs1360780 in the FKBP5 gene and childhood maltreatment, influencing a variety of clinical outcomes...

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Bibliographic Details
Published in:	Psychoneuroendocrinology Vol. 128; p. 105221
Main Authors:	Ferrer, Alex, Soria, Virginia, Salvat-Pujol, Neus, Martorell, Lourdes, Armario, Antonio, Urretavizcaya, Mikel, Gutiérrez-Zotes, Alfonso, Monreal, José Antonio, Crespo, José Manuel, Massaneda, Clara, Vilella, Elisabet, Palao, Diego, Menchón, José Manuel, Labad, Javier
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-06-2021
Subjects:	Adverse Childhood Experiences - psychology Childhood maltreatment Cognition Cognition - physiology FKBP5 Genotype HPA axis Humans Hypothalamo-Hypophyseal System - physiology Pituitary-Adrenal System - physiology Social cognition Tacrolimus Binding Proteins - genetics Childhood maltreatment HPA axis Cognition FKBP5 Social cognition
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