Oral colon-targeted responsive alginate/hyaluronic acid-based hydrogel propels the application of infliximab in colitis

Currently, commercialized infliximab (IFX) has rapidly propelled the clinical treatment of IBD, however, its inherent attributes, such as off-target effects and rapid metabolism, severely limit practical applications. Moreover, high doses injection of IFX can result in IBD treatment failure, which m...

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Bibliographic Details

Published in:	International journal of biological macromolecules Vol. 249; p. 125952
Main Authors:	Huai, Manxiu, Pei, Mingliang, Pan, Jiaxing, Zhu, Yun, Chen, Yingwen, Du, Peng, Duan, Yanming, Xu, Huixiong, Ge, Wensong
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 30-09-2023
Subjects:	IBD Infliximab delivery Oral hydrogel IBD Infliximab delivery Oral hydrogel
Online Access:	Get full text
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