Case of Ulcerative Colitis Associated with Oesophageal Ulcer

• Published in: Journal of international medical research Vol. 28; no. 4; pp. 191 - 196
• Main Authors: Asakawa, A, Kojima, Y, Fujii, E, Ohtaka, M, Shimazaki, R, Sato, T, Nakamura, T, Morozumi, A, Akahane, Y, Fujino, MA
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01-07-2000; Cambridge Medical Publications
• Subjects: Adolescent; Anti-Inflammatory Agents - therapeutic use; Biological and medical sciences; Colitis, Ulcerative - complications; Colitis, Ulcerative - diagnosis; Colitis, Ulcerative - drug therapy; Endoscopy, Gastrointestinal; Esophageal Diseases - complications; Esophageal Diseases - diagnosis; Esophageal Diseases - drug therapy; Esophagoscopy; Esophagus; Female; Gastroenterology. Liver. Pancreas. Abdomen; Humans; Medical sciences; Other diseases. Semiology; Prednisolone - therapeutic use; Stomach. Duodenum. Small intestine. Colon. Rectum. Anus; Ulcer - complications; Ulcer - diagnosis; Ulcer - drug therapy; Oesophagogastroduodenoscopy; Ulcerative colitis; Oesophageal ulcer; Case study; Human; Esophageal disease; Digestive diseases; Intestinal disease; Complication; Ulcer; Inflammatory disease; Esophagus
• ISSN: 0300-0605; 1473-2300
• DOI: 10.1177/147323000002800405

A case of ulcerative colitis complicated by oesophageal ulcers is reported. A woman was admitted to our hospital because of exacerbations of ulcerative colitis both in 1992 (aged 15 years) and 1995 (aged 18 years). When she was admitted in 1995 she complained of bloody diarrhoea, sore throat and pain on swallowing. Oesophagogastroduodenoscopy revealed oesophageal ulcers. Oesophageal pH monitoring (24-h) showed no evidence of gastro-oesophageal reflux disease. After the patient was treated with oral prednisolone she showed considerable improvement clinically and endoscopically. Initial dosage was 60 mg/day, and 1 week later, the dosage was gradually dropped since the patient responded favourably. The improvement of the oesophageal lesions coincided with the remission of ulcerative colitis. The oesophageal ulcers are, therefore, thought to be an extracolonic manifestation of ulcerative colitis.