Short-term preseasonal immunotherapy: is early clinical efficacy related to the basophil response?

An aluminum hydroxide-adsorbed depot allergoid preparation of six-grass pollen allergens has been developed for short-term preseasonal immunotherapy in pollinosis. However, only limited knowledge exists about its immunological and clinical effects. The aim of this study was to evaluate the basophil...

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Bibliographic Details
Published in:	International archives of allergy and immunology Vol. 164; no. 3; p. 237
Main Authors:	Kepil Özdemir, Seçil, Sin, Betül Ayşe, Güloğlu, Deniz, İkincioğulları, Aydan, Gençtürk, Zeynep, Mısırlıgil, Zeynep
Format:	Journal Article
Language:	English
Published:	Switzerland 01-01-2014
Subjects:	Adult Allergens - immunology Antigens, Plant - therapeutic use Basophils - immunology Desensitization, Immunologic - methods Double-Blind Method Female Humans Immunoglobulin E - blood Immunoglobulin G - blood Male Phleum - immunology Phosphoric Diester Hydrolases - biosynthesis Phosphoric Diester Hydrolases - immunology Placebos Plant Extracts - therapeutic use Pollen - immunology Pyrophosphatases - biosynthesis Pyrophosphatases - immunology Rhinitis, Allergic, Seasonal - immunology Rhinitis, Allergic, Seasonal - therapy
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