Voriconazole-loaded self-nanoemulsifying drug delivery system (SNEDDS) to improve transcorneal permeability

The aim of this study was to develop self- nanoemulsifying drug delivery system (SNEDDS) to improve the transcorneal permeability of voriconazole. A 'mixture design around a reference mixture' approach was applied. This latter included four components, namely, isopropyl myristate, PEG 400,...

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Bibliographic Details
Published in:	Pharmaceutical development and technology Vol. 25; no. 6; pp. 694 - 703
Main Authors:	Rasoanirina, Bakoliarisoa Nivomalala Voahangy, Lassoued, Mohamed Ali, Kamoun, Amel, Bahloul, Badr, Miladi, Karim, Sfar, Souad
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 02-07-2020
Subjects:	Animals Antifungal Agents - administration & dosage Antifungal Agents - metabolism Cattle Cornea - drug effects Cornea - metabolism Drug Delivery Systems - methods Emulsions - administration & dosage Emulsions - metabolism mixture design Mycotic keratitis Nanoparticles - administration & dosage Nanoparticles - metabolism Organ Culture Techniques Permeability - drug effects response trace SNEDDS transcorneal permeability voriconazole Voriconazole - administration & dosage Voriconazole - metabolism voriconazole mixture design SNEDDS Mycotic keratitis response trace transcorneal permeability
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