The influence of growth and E. coli endotoxaemia on amoxicillin pharmacokinetics in turkeys

1. This experiment aimed to determine if the pharmacokinetics of amoxicillin (AMO) was affected by rapid growth or intravenous (i.v.) injection of Escherichia coli lipopolysaccharide (LPS). 2. Turkeys of 2.0, 5.5 and 12.0 kg were administered i.v. or orally with AMO sodium at the dose of 15 mg/kg. A...

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Bibliographic Details
Published in:	British poultry science Vol. 58; no. 4; pp. 462 - 468
Main Authors:	Poźniak, B., Pasławska, U., Motykiewicz-Pers, K., Świtała, M.
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 04-07-2017
Subjects:	Administration, Intravenous - veterinary Administration, Oral Amoxicillin Amoxicillin - pharmacokinetics Animals Anti-Bacterial Agents - pharmacokinetics Endotoxemia - drug therapy Endotoxemia - microbiology Endotoxemia - veterinary Escherichia coli - physiology Escherichia coli Infections - drug therapy Escherichia coli Infections - microbiology Escherichia coli Infections - veterinary growth haemodynamics Half-Life Injections, Intravenous - veterinary lipopolysaccharide Lipopolysaccharides Male pharmacokinetics Poultry Diseases - drug therapy Poultry Diseases - metabolism Random Allocation turkeys Turkeys - growth & development pharmacokinetics growth lipopolysaccharide haemodynamics Amoxicillin turkeys
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