Characterization of bone mineral composition in the proximal tibia of cynomolgus monkeys: Effect of ovariectomy and nandrolone decanoate treatment

Life postmenopausal women, ovariectomized cynomolgus monkeys (Macaca fascicularis) experience accelerated loss of bone mass. Treatment of ovariectomized monkeys with nandrolone decanoate results in an increase in bone mass to levels comparable to those of intact animals. The changes in bone composit...

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Bibliographic Details
Published in:	Bone (New York, N.Y.) Vol. 30; no. 3; pp. 492 - 497
Main Authors:	HUANG, R. Y, MILLER, L. M, CARLSON, C. S, CHANCE, M. R
Format:	Journal Article
Language:	English
Published:	New York, NY Elsevier Science 01-03-2002
Subjects:	Anabolic Agents - pharmacology Anabolic Agents - therapeutic use Animals Biological and medical sciences Bone Density - drug effects Bone Density - physiology Estrogens - deficiency Female Fundamental and applied biological sciences. Psychology Macaca fascicularis Nandrolone - analogs & derivatives Nandrolone - pharmacology Nandrolone - therapeutic use Nandrolone Decanoate Ovariectomy - statistics & numerical data Skeleton and joints Tibia - drug effects Tibia - physiology Vertebrates: osteoarticular system, musculoskeletal system Steroid Animal model Diseases of the osteoarticular system Monkey Macaca fascicularis Bone disease Osteoarticular system Osteoporosis Nandrolone decanoate Mineralization Tibia Surgery Primates Simioidea Female Biological effect Content analysis Ovariectomy Treatment efficiency Experimental study Upper extremity Vertebrata Chemotherapy Mammalia Treatment Bone
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