Nanoencapsulated fluoride as a remineralization option for dental erosion: an in vitro study

• Published in: Acta odontologica Scandinavica Vol. 79; no. 5; p. 321
• Main Authors: de Lavôr, Juliane Rolim, Fernandes, Nayanna Lana Soares, de Sousa, Elizabeth Barreto Galvão, da Cunha, Juliellen Luiz, Meira, Ingrid Andrade, Correia Sampaio, Fábio, de Oliveira, Andressa Feitosa Bezerra
• Format: Journal Article
• Language: English
• Published: England 04-07-2021
• Subjects: Cariostatic Agents; Dental Enamel; Dentifrices; Fluorides; Hardness; Humans; Sodium Fluoride; Tooth Erosion - drug therapy; Tooth Erosion - prevention & control; Tooth Remineralization; Dental erosion; nanotechnology; fluoride; dentifrices; tooth remineralization
• ISSN: 1502-3850
• DOI: 10.1080/00016357.2020.1849793

To compare the
performance of different dentifrices indicated for dental erosion and a new dentifrice with controlled fluoride release system (NanoF) in terms of surface microhardness remineralization in enamel erosion lesions.
72 human enamel specimens were divided into 6 groups (
 = 12): PC (100% NaF - positive control); NC (Placebo - negative control); 50%nF (50% NanoF + 50% free NaF), 100%nF (100% NanoF); PN (Sensodyne
ProNamel™) and AG (Colgate
Sensitive Pro-Relief™). A surface microhardness analysis was performed before (SH
) and after (SH
) the erosion lesion formation. The blocks were submitted to a 5-day de-remineralization cycling model, consisting of 90 s immersion on 0.1% citric acid (4x/day) and 1 min treatment with dentifrice slurries along with 1 mL/block of human saliva (2x/day). Lastly, the final surface microhardness analysis (SH
) was measured and the percentage of surface microhardness remineralization (%SMH
) was calculated. Data were analysed with 2-way ANOVA and Tukey's test (
 < .05).
Statistically significant differences were observed for SH
and %SMH
between NC and AG with the other groups (
 < .05). The best %SMH
from the experimental groups was found in 100%nF and PN.
Dentifrices with NanoF exhibited a surface microhardness remineralization similar to sodium fluoride (PC). Therefore, NanoF dentifrice can be an alternative to prevent and treat patients with dental erosion.