Development of patient-derived orthotopic xenografts from metastatic colorectal cancer in nude mice

Liver metastasis is the major cause of death for patients with colorectal cancer. Despite treatment with surgery and chemotherapy, patient outcomes are quite unfavourable. Thus, there is an urgent need to develop new treatment strategies with the associated establishment of good animal models. Metas...

Full description

Bibliographic Details

Published in:	Journal of drug targeting Vol. 27; no. 9; pp. 943 - 949
Main Authors:	Roque-Lima, Bruno, Roque, Caroline Correa de Tulio Augusto, Begnami, Maria Dirlei, Peresi, Patricia, Lima, Eduardo Nobrega Pereira, Mello, Celso Abdon Lopes de, Coimbra, Felipe JoséFernandez, Chojniak, Rubens, Goss Santos, Tiago
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 21-10-2019
Subjects:	colorectal cancer metastasis Orthotopic xenograft preclinical model Orthotopic xenograft colorectal cancer preclinical model metastasis
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!