Absence of Abnormalities of c-kit or Its Ligand in Two Patients With Diamond-Blackfan Anemia

As Diamond-Blackfan anemia shares clinical features with W and Steel defects in mice, we investigated the possibility that this human disorder might result from an abnormality of the c-kit receptor or its ligand, stem cell factor (SCF). For these studies, full nucleotide sequences for coding regions...

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Bibliographic Details
Published in:	Blood Vol. 79; no. 1; pp. 25 - 28
Main Authors:	Abkowitz, Janis L., Broudy, Virginia C., Bennett, Larry G., Zsebo, Krisztina M., Martin, Frank H.
Format:	Journal Article
Language:	English
Published:	Washington, DC Elsevier Inc 01-01-1992 The Americain Society of Hematology
Subjects:	Adult Anemias. Hemoglobinopathies Base Sequence Biological and medical sciences Bone Marrow - metabolism Diseases of red blood cells DNA - genetics Fanconi Anemia - genetics Fanconi Anemia - metabolism Female Hematologic and hematopoietic diseases Hematopoietic Cell Growth Factors - genetics Hematopoietic Cell Growth Factors - metabolism Humans Male Medical sciences Molecular Sequence Data Polymerase Chain Reaction Proto-Oncogene Proteins - genetics Proto-Oncogene Proteins c-kit Receptors, Cell Surface - genetics Stem Cell Factor Human Ligand Pathogenesis C-Onc gene Hemopathy Blackfan Diamond disease Congenital disease Protooncogene Biological receptor
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