Carcinogenesis of Male Oral Submucous Fibrosis Alters Salivary Microbiomes

Most oral squamous cell carcinoma (OSCC) tumors arise from oral premalignant lesions. Oral submucous fibrosis (OSF), usually occurring in male chewers of betel quid, is a premalignant stromal disease characterized by a high malignant transformation rate and high prevalence. Although a relationship b...

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Bibliographic Details
Published in:	Journal of dental research Vol. 100; no. 4; pp. 397 - 405
Main Authors:	Chen, M.Y., Chen, J.W., Wu, L.W., Huang, K.C., Chen, J.Y., Wu, W.S., Chiang, W.F., Shih, C.J., Tsai, K.N., Hsieh, W.T., Ho, Y.H., Wong, T.Y., Wu, J.H., Chen, Y.L.
Format:	Journal Article
Language:	English
Published:	Los Angeles, CA SAGE Publications 01-04-2021 SAGE PUBLICATIONS, INC
Subjects:	Artificial Intelligence Carcinogenesis Carcinoma, Squamous Cell Fibrosis Genetic transformation Head and Neck Neoplasms Humans Male Malignancy Methionine Microbiomes Microbiota Mouth Neoplasms Next-generation sequencing Oral squamous cell carcinoma Oral Submucous Fibrosis Ornithine Phylogenetics Phylogeny Porphyromonas Prevotella RNA, Ribosomal, 16S - genetics rRNA 16S Species richness Squamous cell carcinoma Stochasticity Tumors microbiota saliva precancerous conditions machine learning biomarker dysbiosis
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