A UPLC–MS/MS method for the quantitation of Ulipristal acetate in human serum

The progesterone receptor modulator, Ulipristal acetate (UPA) has proven to be an effective emergency contraceptive. Conflicting data has been reported that suggests different efficacy of the drug in different populations, which may be explained by the systemic exposure to the drug. A UPLC–MS/MS met...

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Bibliographic Details

Published in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Vol. 1059; pp. 43 - 48
Main Authors:	Nandakumar, Renu, Praditpan, Piyapa, Westhoff, Carolyn L., Cremers, Serge
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-08-2017
Subjects:	Calibration Chromatography, High Pressure Liquid - methods Drug Stability Humans LC–MS/MS Norpregnadienes - blood Pharmacokinetics Reproducibility of Results Tandem Mass Spectrometry - methods Ulipristal acetate Validation Validation Pharmacokinetics LC–MS/MS Ulipristal acetate
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