The effect of Ipomoea carnea on maternal reproductive outcomes and fetal and postnatal development in rats

Ipomoea carnea is a toxic plant found in Brazil and other tropical countries. The plant contains the alkaloids calystegines and swainsonine, which inhibit key cellular enzymes and cause systematic cell death. It is known that swainsonine is excreted in the amniotic fluid of dams exposed to the plant...

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Bibliographic Details
Published in:	Toxicon (Oxford) Vol. 190; pp. 3 - 10
Main Authors:	Gotardo, André Tadeu, Lippi, Luciana Lucinio, Violin, Kalan Bastos, Andrade Forell Bevilacqua, Estela Maris, Górniak, Silvana Lima
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 30-01-2021
Subjects:	Alkaloids Animals Birth defects Brazil Female Fetus Goats Ipomoea Ipomoea carnea Kidney Liver Male Placental toxicity Plant Extracts - toxicity Plant Leaves Plants, Toxic Pregnancy Rats Reproduction Reproductive toxicology Swainsonine Swainsonine - toxicity Toxicity Tests Tropanes Brazil Birth defects Placental toxicity Reproductive toxicology Ipomoea carnea Swainsonine
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