Test guidelines for assessment of skin compatibility of cosmetic finished products in man

• Published in: Food and chemical toxicology Vol. 34; no. 7; pp. 651 - 660
• Main Authors: Walker, A.P., Basketter, D.A., Baverel, M., Diembeck, W., Matthies, W., Mougin, D., Paye, M., Röthlisberger, R., Dupuis, J.
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 1996; New York, NY Elsevier Science
• Subjects: Biological and medical sciences; Domestic and cosmetic products toxicology; Medical sciences; Toxicology; Europe; Cosmetic; Human; Skin disease; Investigation method; Toxicity; Alternative method; Skin; Recommendation
• ISSN: 0278-6915; 1873-6351
• DOI: 10.1016/0278-6915(96)00029-4

The following guidelines present an alternative, by using humans, to the patch test on rabbits for assessment of the skin irritation potential of cosmetic-finished products. The guidelines were developed by a Task Force of COLIPA, the European Federation of national cosmetic, toiletry and perfumery associations. The guidelines have been discussed with (and amended to take account of comments from) European dermatologists.