Ureteric Obstruction From Malignant Melanoma in Both Right Double Moiety and Left Single Moiety Ureters

• Published in: Urology (Ridgewood, N.J.) Vol. 103; pp. e7 - e8
• Main Authors: March, Brayden, Calopedos, Ross John Spero, Latif, Edward, Ouyang, Rupert
• Format: Journal Article
• Language: English
• Published: United States 01-05-2017
• Subjects: Urology; ureter; metastatic disease; malignant melanoma
• ISSN: 0090-4295; 1527-9995
• DOI: 10.1016/j.urology.2017.02.021

Abstract We report the first documented case of malignant melanoma obstructing ureters of both moieties of a duplex kidney and contralateral single moiety ureter in a 51-year-old male. The patient presented with fever, coryzal symptoms and liver function test derangement several years after two superficial spreading melanomas were excised with clear margins. Ultrasonography demonstrated hydronephroureter in both moieties of a complete right-sided duplex kidney. Retrograde pyelograms showed bilateral hydronephroureter and filling defects in all three ureters. Biopsied tumour cells were positive for S100, Melan A and HMB45. Cutaneous melanoma metastasizing to ureters is a rare phenomenon, and can present a diagnostic challenge to clinicians if clinically silent.