Nutritional regulation of proteinase production in the fungus, Tritirachium album

• Published in: Journal of industrial microbiology & biotechnology Vol. 24; no. 6; pp. 369 - 373
• Main Authors: FORTELIUS, C, MARKKANEN, P
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 01-06-2000; Oxford University Press
• Subjects: Ammonium; Biological and medical sciences; Biotechnology; Carbon; Drinking water; Enzyme engineering; Enzymes; Experiments; Fermentation; Fundamental and applied biological sciences. Psychology; Fungi; Glucose; Hemoglobin; Keratin; Methods. Procedures. Technologies; Microbiology; Nitrates; Nitrogen; Nitrogen sources; Nutrition; Peptones; Production of selected enzymes; Proteins; Sodium; Studies; Tritirachium album; Yeast; Yeasts; Fungi; Peptidases; Regulation(control); Nutrient source; Enzyme; Production; Microorganism culture; Hydrolases; Nitrogen; Carbon; Thallophyta
• ISSN: 1367-5435; 1476-5535
• DOI: 10.1038/sj.jim.7000012

The fungus, Tritirachium album, produces a number of proteinases under proper conditions. We have studied the nutritional regulation mechanisms for proteinase production in the mold, i.e. the effects of carbon and nitrogen sources, and the influence of starvation. Proteinase production was induced when the nitrogen source was an exogenous protein or peptide, such as peptones or yeast extract. The production rate was affected by the amount of available inducing substrate. Inorganic nitrogen compounds, i.e., ammonium or nitrate salts, had a repressing effect on the production. Production was not induced if a detectable concentration of glucose or sucrose was present in the medium. Starvation did not trigger proteinase production. Journal of Industrial Microbiology & Biotechnology (2000) 24, 369-373.[PUBLICATION ABSTRACT]