Global, regional, and national burden of other musculoskeletal disorders 1990–2017: results from the Global Burden of Disease Study 2017

• Published in: Rheumatology (Oxford, England) Vol. 60; no. 2; pp. 855 - 865
• Main Authors: Safiri, Saeid, Kolahi, Ali Asghar, Cross, Marita, Carson-Chahhoud, Kristin, Almasi-Hashiani, Amir, Kaufman, Jay, Mansournia, Mohammad Ali, Sepidarkish, Mahdi, Ashrafi-Asgarabad, Ahad, Hoy, Damian, Collins, Gary, Woolf, Anthony D, March, Lyn, Smith, Emma
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01-02-2021
• Subjects: Disabled Persons - statistics & numerical data; Female; Global Burden of Disease - methods; Global Burden of Disease - statistics & numerical data; Global Burden of Disease - trends; Global Health - statistics & numerical data; Humans; Incidence; Life Expectancy - trends; Male; Middle Aged; Musculoskeletal Diseases - epidemiology; Prevalence; Quality-Adjusted Life Years; Risk Factors; Socioeconomic Factors; osteomyelitis; prevalence; epidemiology; systemic lupus erythematosus; joint diseases; incidence; other musculoskeletal disorders; burden
• ISSN: 1462-0324; 1462-0332
• DOI: 10.1093/rheumatology/keaa315

Abstract
Objectives
To describe the level and trends of point prevalence, deaths and disability-adjusted life years (DALYs) for other musculoskeletal (MSK) disorders, i.e. those not covered by specific estimates generated for RA, OA, low back pain, neck pain and gout, from 1990 to 2017 by age, sex and sociodemographic index.
Methods
Publicly available modelled estimates from the Global Burden of Disease (GBD) 2017 study were extracted and reported as counts and age-standardized rates per 100 000 population for 195 countries and territories between 1990 and 2017.
Results
Globally, the age-standardized point prevalence estimates and deaths rates of other MSK disorders in 2017 were 4151.1 and 1.0 per 100 000. This was an increase of 3.4% and 7.2%, respectively. The age-standardized DALY rate in 2017 was 380.2, an increase of 3.4%. The point prevalence estimate was higher among females and increased with age. This peaked in the 65–69 year age group for both females and males in 2017, followed by a decreasing trend for both sexes. At the national level, the highest age-standardized point prevalence estimates in 2017 were seen in Bangladesh, India and Nepal. The largest increases in age-standardized point prevalence estimates were observed in Romania, Croatia and Armenia.
Conclusion
The burden of other MSK disorders is proven to be substantial and increasing worldwide, with a notable intercountry variation. Data pertaining to specific diseases within this overarching category are required for future GBD MSK estimates. This would enable policymakers to better allocate resources and provide interventions appropriately.