Parameters of oxidative stress, DNA damage and DNA repair in type 1 and type 2 diabetes mellitus

Objectives: (i) to determine the extent of oxidative stress and DNA damage and repair using a panel of selected markers in patients with type 1 and type 2 diabetes mellitus (T1DM, T2DM), (ii) to find their possible relationships with diabetes compensation and duration, and finally (iii) to test for...

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Bibliographic Details
Published in:	Archives of physiology and biochemistry Vol. 117; no. 4; pp. 222 - 230
Main Authors:	Pácal, Lukáš, Varva ovská, Jana, Rušavý, Zden k, Lacigová, Silva, Št tina, Rudolf, Racek, Jaroslav, Pomaha ová, Renata, Tanhäuserová, Veronika, Ka ková, Kate ina
Format:	Journal Article
Language:	English
Published:	Colchester Informa Healthcare 01-10-2011 Taylor & Francis Informa
Subjects:	Adult Aged Alleles antioxidant enzymes Biological and medical sciences Case-Control Studies Catalase - blood Catalase - genetics Child Czech Republic Diabetes Diabetes Mellitus, Type 1 - blood Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 2 - blood Diabetes Mellitus, Type 2 - genetics DNA Damage DNA Glycosylases - blood DNA Glycosylases - genetics DNA Repair Female Fundamental and applied biological sciences. Psychology Gene Frequency Glutathione - blood Glutathione Peroxidase - blood Humans Male Malondialdehyde - blood Middle Aged Oxidative Stress Polymorphism, Genetic single strand breaks Superoxide Dismutase - blood Superoxide Dismutase - genetics Vertebrates: anatomy and physiology, studies on body, several organs or systems Czech Republic Endocrinopathy Type 2 diabetes Immunopathology Oxidative stress Enzyme Autoimmune disease Metabolic diseases antioxidant enzymes Antioxidant DNA repair Vertebrata Mammalia Type 1 diabetes DNA single strand breaks Diabetes Repair
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