LncRNA SOCS2-AS1 promotes the progression of glioma via regulating ITGB1 expression

•The upregulation of SOCS2-AS1 is associated with prognosis in gliomas.•Knockdown of SOCS2-AS1 inhibits the growth of glioma cell.•SOCS2-AS1 is associated with ECM-receptor interaction signaling pathway.•SOCS2-AS1 regulate ITGB1 express in glioma.•ITGB1 mediates the tumor-suppressive effects of SOCS...

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Bibliographic Details
Published in:	Neuroscience letters Vol. 765; p. 136248
Main Authors:	Wu, Dejun, Sun, Jinzhang, Wang, Hongliang, Ma, Chunchun
Format:	Journal Article
Language:	English
Published:	Ireland Elsevier B.V 20-11-2021
Subjects:	Astrocytes Brain - pathology Brain Neoplasms - diagnosis Brain Neoplasms - genetics Brain Neoplasms - mortality Brain Neoplasms - pathology Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics Computational Biology Datasets as Topic Gene Expression Regulation, Neoplastic Gene Knockdown Techniques Glioma Glioma - diagnosis Glioma - genetics Glioma - mortality Glioma - pathology Humans Integrin beta1 - genetics ITGB1 lncRNAs Neoplasm Grading Neoplasm Invasiveness - genetics Prognosis RNA, Long Noncoding - genetics RNA, Long Noncoding - metabolism SOCS2-AS1 Survival Rate Up-Regulation lncRNAs ITGB1 Glioma SOCS2-AS1
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