Treatment of Latent Tuberculosis Infection in Children

Treatment of Latent Tuberculosis Infection in Children

Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide)....

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Bibliographic Details
Published in:Journal of the Pediatric Infectious Diseases Society Vol. 2; no. 3; pp. 248 - 258
Main Authors: Cruz, Andrea T., Ahmed, Amina, Mandalakas, Anna M., Starke, Jeffrey R.
Format: Journal Article
Language:English
Published: England Oxford University Press 01-09-2013
Subjects:
Adherence
Latent Tuberculosis Infection
Directly Observed Preventive Therapy
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Summary:Treatment of latent tuberculosis infection (LTBI) is an effective way of preventing future cases of tuberculosis disease. We review pediatric and adult studies of LTBI treatment (isoniazid and rifampin monotherapy, isoniazid plus rifampin, isoniazid plus rifapentine, and rifampin plus pyrazinamide). Based upon this review and our pediatric experience, we can offer recommendations for routine (isoniazid) and alternative courses of therapy.
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ISSN:2048-7193
2048-7207
DOI:10.1093/jpids/pit030