Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide

Colorimetric Technique for Antimony Detection Based on the Use of Gold Nanoparticles Conjugated with Poly-A Oligonucleotide

A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afford...

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Bibliographic Details
Published in:Applied sciences Vol. 9; no. 22; p. 4782
Main Authors: Berlina, Anna N., Komova, Nadezhda S., Zherdev, Anatoly V., Gaur, Mulayam S., Dzantiev, Boris B.
Format: Journal Article
Language:English
Published: Basel MDPI AG 01-11-2019
Subjects:
Antimony
Aptamers
Coefficient of variation
color change
Colorimetry
Drinking water
Gold
gold nanoparticles
heavy metal analyses
Ions
Nanoparticles
oligonucleotide
Photometry
St Louis Missouri
United Kingdom > UK
United States > US
Japan
Russia
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Summary:A simple and rapid positive–negative colorimetric approach to determine the presence of antimony ions based on the use of gold nanoparticles conjugated with oligonucleotide (poly-A sequence) is developed. Colorimetric measurements reveal that the aggregates of modified gold nanoparticles were afforded after adding antimony ions, thus changing the solution color from pink to blue. The results of aptamer’s interaction on the gold nanoparticle surface with the target analyte can be detected either by photometry or by the naked eye. The realized assay provides rapid (2 min), sensitive (detection limit 10 ng/mL), specific, and precise (variation coefficient less than 3.8%) detection of antimony (III) in drinking water.
ISSN:2076-3417
2076-3417
DOI:10.3390/app9224782