Utility of nuclear matrix protein (NMP22) in the detection of recurrent bladder cancer

This article examines the Nuclear Matrix Protein (NMP22) urine test for recurrent bladder cancer detection. Studies with NMP22 are compared to cytology for sensitivity and specificity. False positives and false negatives do occur, and consequences of these are discussed. Speculations are made regard...

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Bibliographic Details
Published in:	Urologic clinics of North America Vol. 27; no. 1; p. 47
Main Authors:	Grocela, J A, McDougal, W S
Format:	Journal Article
Language:	English
Published:	United States 01-02-2000
Subjects:	Biomarkers, Tumor - metabolism Humans Neoplasm Invasiveness Neoplasm Recurrence, Local Neoplasm Staging Nuclear Proteins - metabolism Sensitivity and Specificity Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology Urologic Neoplasms - metabolism
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Summary:	This article examines the Nuclear Matrix Protein (NMP22) urine test for recurrent bladder cancer detection. Studies with NMP22 are compared to cytology for sensitivity and specificity. False positives and false negatives do occur, and consequences of these are discussed. Speculations are made regarding possible future uses of this test.
ISSN:	0094-0143
DOI:	10.1016/S0094-0143(05)70233-0