Bosentan in Clinical Practice for Treating Digital and Other Ischemic Ulcers in Spanish Patients with Systemic Sclerosis: IBER-DU Cohort Study

To describe treatment outcomes and safety experience with bosentan in patients with systemic sclerosis (SSc) and digital ulcers (DU), in a clinical setting in Spain. This was a multicenter, noninterventional retrospective cohort study. Data were collected retrospectively from patients with DU, with...

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Bibliographic Details
Published in:	Journal of rheumatology Vol. 38; no. 8; pp. 1631 - 1635
Main Authors:	ROMAN IVORRA, Jose Andrés, SIMEON, Carmen Pilar, ALEGRE SANCHO, Juan José, EGURBIDE, Maria Victoria, CASTILLO, Maria Jesús, LLORIA, Xavier, FONOLLOSA, Vicent
Format:	Journal Article
Language:	English
Published:	Toronto, ON Journal of Rheumatology Publishing 01-08-2011
Subjects:	Antihypertensive Agents - therapeutic use Biological and medical sciences Cohort Studies Diseases of the osteoarticular system Humans Hypertension - drug therapy Ischemia - pathology Medical sciences Randomized Controlled Trials as Topic Retrospective Studies Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis Scleroderma, Systemic - complications Scleroderma, Systemic - drug therapy Scleroderma, Systemic - pathology Skin Ulcer - drug therapy Skin Ulcer - etiology Skin Ulcer - pathology Spain Sulfonamides - therapeutic use Treatment Outcome Spain Human Immunopathology Connective tissue disease OBSERVATIONAL STUDY Skin disease Endothelin SYSTEMIC SCLEROSIS Rheumatology Autoimmune disease Cardiovascular disease Bosentan Treatment Ischemia DIGITAL ULCERS Cohort study Systemic disease Peptidergic receptor Ulcer Antagonist Scleroderma Endothelin receptor
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