High-Throughput, Biosensor-Based Approach to Examine Bone Morphogenetic Protein (BMP)-Receptor Interactions

Binding of a BMP to its cognate cell surface receptors is the initiating step in the BMP signaling cascade. Thus, knowing which BMP-receptor complexes form is vital for understanding the physiological activities of a particular BMP. Here, we describe a surface plasmon resonance (SPR)-based, high-thr...

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Bibliographic Details

Published in:	Methods in molecular biology (Clifton, N.J.) Vol. 1891; p. 37
Main Authors:	Aykul, Senem, Martinez-Hackert, Erik
Format:	Journal Article
Language:	English
Published:	United States 2019
Subjects:	Biosensing Techniques Bone Morphogenetic Protein Receptors - genetics Bone Morphogenetic Protein Receptors - metabolism Bone Morphogenetic Proteins - genetics Bone Morphogenetic Proteins - metabolism High-Throughput Screening Assays Protein Interaction Mapping Surface Plasmon Resonance TGF-β Surface plasmon resonance Bone morphogenetic protein Activin Protein–protein interaction s
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