Baeyer-Villiger Oxidation of the Bicyclo[2.2.2]octanone System Revisited: Searching for a Modular Construction of Heavily Substituted Cyclohexanes Based on m-CPBA Mediated Selective Oxygen Insertion

Described herein is the use of Baeyer–Villiger oxidation for the selective insertion of oxygen into a variously substituted bicyclo[2.2.2]octanone system, synthesized by a consecutive domino process. By using the appropriate sequence of steps and starting from common intermediate 2a, six‐membered ri...

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Bibliographic Details
Published in:	European Journal of Organic Chemistry Vol. 2007; no. 24; pp. 4116 - 4123
Main Authors:	Finet, Laure, Dakir, Mohamed, Castellote, Isabel, Arseniyadis, Siméon
Format:	Book Review Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag 01-08-2007 WILEY‐VCH Verlag Wiley-VCH Verlag
Subjects:	Chemical Sciences Configuration reversal Domino reactions/ Baeyer-Villiger oxidation Organic chemistry Quaternary centers Ring-system interchange
Online Access:	Get full text
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Summary:	Described herein is the use of Baeyer–Villiger oxidation for the selective insertion of oxygen into a variously substituted bicyclo[2.2.2]octanone system, synthesized by a consecutive domino process. By using the appropriate sequence of steps and starting from common intermediate 2a, six‐membered ring systems with appropriate substituents that could serve as surrogates for several functionalities could be accessed.(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Bibliography:	istex:3F15135F1DD55BE41A0372EF16EAC981189C55A0 ArticleID:EJOC200700321 ark:/67375/WNG-N37VNVVL-W
ISSN:	1434-193X 1099-0690
DOI:	10.1002/ejoc.200700321