Progress toward universal health coverage in Vietnam: Evidence on dispensing trends of diabetes medications from 2015 to 2021

•Nationally, the total mass/doses of all oral antidiabetic drugs significantly increased from 2015 to 2021.•Metformin remains the most prescribed antidiabetics, with the total mass increased approximately three times over the study period.•Gliclazide ranked second despite the cautions for using Sulf...

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Published in:Diabetes research and clinical practice Vol. 212; p. 111691
Main Authors: Dang, Anh Kim, Vu, Binh Ngan, Lam, Toi Phung, Ho, Thanh Kim Thi, Nguyen, Anh Kieu Thi, Le, Huong Thi, Mamun, Abdullah A., Phung, Dung, Thai, Phong K.
Format: Journal Article
Language:English
Published: Ireland Elsevier B.V 01-06-2024
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Summary:•Nationally, the total mass/doses of all oral antidiabetic drugs significantly increased from 2015 to 2021.•Metformin remains the most prescribed antidiabetics, with the total mass increased approximately three times over the study period.•Gliclazide ranked second despite the cautions for using Sulfonylureas in the latest guidelines.•Changes in treatment policies can contribute to the increase in the use of diabetes medications over time.•The significant increase in diabetes medication dispensing is a good indicator of progress in achieving universal coverage for diabetes treatment in Vietnam. This study aims to investigate the trends in treatment coverage through dispensing diabetes medications in Vietnam from 2015 to 2021. The findings will serve to inform health policies to mitigate the health burden of Type 2 diabetes mellitus (T2DM). We collected information on major antidiabetic medicines from General Department of Vietnam Customs and payments for antidiabetics via the National Health Insurance Program. We applied ordinary least squares models, accounting for economic and health outcome characteristics, to estimate the association between the annual mass of medications and related factors. Nationally, the total mass/doses of all antidiabetic drugs increased rapidly from 2015 to 2021, based on both databases. Metformin was the most frequently prescribed medicine, with the total mass increasing nearly threefold over the study period. Gliclazide, a Sulfonylureas drug, ranked second. In the multivariate regression analysis, a one-unit increase in adults with diabetes (in 1,000 s) was associated with 0.11 % (95 %CI = 0.0005; 0.0076) and 0.13 % (95%CI = 0.0007; 0.0242) higher mass of Metformin and Glimepiride, respectively. Our data suggested that policies changes were related to significant increase in antidiabetic medication dispenses in Vietnam. The high treatment coverage indicates impressive progress in achieving universal health coverage in Vietnam, meeting the UN Sustainable Development Goal (SDG).
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ISSN:0168-8227
1872-8227
DOI:10.1016/j.diabres.2024.111691