The utility of maternal mean platelet volume levels for early onset neonatal sepsis prediction of term infants

• Published in: Ginekologia polska Vol. 88; no. 6; pp. 312 - 314
• Main Authors: Cekmez, Yasemin, Dizdar Güleçoğlu, Merve, Özcan, Cemile, Karadeniz, Leyla, Kıran, Gürkan
• Format: Journal Article
• Language: English
• Published: Poland Wydawnictwo Via Medica 01-01-2017
• Subjects: Adult; Biomarkers - blood; Female; Humans; Infant, Newborn; Leukocyte Count; Maternal-Fetal Exchange - physiology; Mean Platelet Volume - classification; Neonatal Sepsis - blood; Neonatal Sepsis - diagnosis; Platelet Count; Pregnancy; Prenatal Diagnosis; Retrospective Studies; Risk Factors; ROC Curve; Sepsis; infection; mean platelet volum; early onset neonatal sepsis; pregnancy
• ISSN: 0017-0011; 2543-6767
• DOI: 10.5603/GP.a2017.0058

This study is aimed to evaluate the role of maternal mean platelet volume (MPV) levels for antenatal prediction marker of early onset neonatal sepsis in term infants born to mothers who have low infection risk.
A total of 62 pregnant women who gave birth in our hospital and whose neonates were admitted to a third level Neonatal Intensive Care Unit due to confirmed neonatal sepsis between January 2010 and May 2016 were selected as a study group. Within the same period, 68 women who gave birth to healthy neonates were enrolled as a control group. We compared maternal MPV values which were evaluated before delivery. The receiver operating characteristic (ROC) curves were drawn to evaluate the values maternal MPV in the diagnosis of neonatal sepsis.
MPV levels were detected statistically higher in the study group than the control group (8.27 ± 1.85 vs. 8.98 ± 1.16) (p = 0.001).
The maternal serum MPV level is a clinically useful, non-invasive and reliable marker in antenatal prediction of EOS.