Membrane potassium currents in human radial artery and their regulation by nitric oxide donor

The human radial artery has demonstrated superior long-term results as a graft in coronary bypass surgery, but undesirable post-surgical spasm limits its clinical application. Few have examined its excitatory properties, especially the underlying ion channel mechanisms. In this study, we investigate...

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Bibliographic Details
Published in:	Cardiovascular research Vol. 71; no. 2; pp. 383 - 392
Main Authors:	Zhang, Yongde, Tazzeo, Tracy, Chu, Victor, Janssen, Luke J
Format:	Journal Article
Language:	English
Published:	England 15-07-2006
Subjects:	4-Aminopyridine - pharmacology Adult Aged Aged, 80 and over Blotting, Western - methods Female Glyburide - pharmacology Guanylate Cyclase - antagonists & inhibitors Guanylate Cyclase - metabolism Humans In Vitro Techniques Ion Channel Gating - drug effects Male Membrane Potentials - drug effects Middle Aged Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Nitric Oxide Donors - pharmacology Oxadiazoles - pharmacology Patch-Clamp Techniques Penicillamine - analogs & derivatives Penicillamine - pharmacology Peptides - pharmacology Potassium Channel Blockers - pharmacology Potassium Channels - metabolism Potassium Channels, Calcium-Activated - antagonists & inhibitors Potassium Channels, Calcium-Activated - metabolism Potassium Channels, Voltage-Gated - antagonists & inhibitors Potassium Channels, Voltage-Gated - metabolism Quinoxalines - pharmacology Radial Artery Tetraethylammonium Compounds - pharmacology
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