Systematic mapping of nephroureterectomy specimens removed for urothelial cancer: pathological findings and clinical correlations

The nature and extent of mucosal alterations in 30 consecutive surgical specimens removed for urothelial neoplasia were evaluated by systematic mapping. The findings correlated with pertinent pathological, cytological and clinical data. Generally, the grade of the principal neoplasm paralleled the d...

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Bibliographic Details
Published in:	The Journal of urology Vol. 128; no. 2; p. 243
Main Authors:	McCarron, Jr, J P, Chasko, S B, Gray, Jr, G F
Format:	Journal Article
Language:	English
Published:	United States 01-08-1982
Subjects:	Adult Aged Carcinoma in Situ - pathology Carcinoma, Papillary - pathology Epithelium - pathology Female Humans Hyperplasia Kidney - pathology Male Middle Aged Ureter - pathology Ureteral Neoplasms - pathology Urinary Bladder - pathology Urinary Bladder Neoplasms - pathology Urologic Neoplasms - diagnosis Urologic Neoplasms - pathology
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Summary:	The nature and extent of mucosal alterations in 30 consecutive surgical specimens removed for urothelial neoplasia were evaluated by systematic mapping. The findings correlated with pertinent pathological, cytological and clinical data. Generally, the grade of the principal neoplasm paralleled the degree of epithelial disturbance in the grossly normal urothelium, high grade carcinomas being associated consistently with severe changes and low grade cancers with hyperplasia only. Cytological studies reflected accurately the grade of the principal neoplasm, and the presence of concomitant contiguous and remote mucosal abnormalities.
ISSN:	0022-5347
DOI:	10.1016/S0022-5347(17)52871-2