Preparation and Antihypoxic Activity of Complexes of Uracil Derivatives with Dicarboxylic Acids

Preparation and Antihypoxic Activity of Complexes of Uracil Derivatives with Dicarboxylic Acids

Water-soluble low-toxicity complexes of 6-methyluracil and its derivatives with succinic and fumaric acids were synthesized. The synthesized complexes were tested for antihypoxic activity.

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Bibliographic Details
Published in:Pharmaceutical chemistry journal Vol. 48; no. 2; pp. 93 - 96
Main Authors: Gimadieva, A. R., Myshkin, V. A., Mustafin, A. G., Chernyshenko, Yu. N., Borisova, N. S., Zimin, Yu. S., Abdrakhmanov, I. B.
Format: Journal Article
Language:English
Published: Boston Springer US 01-05-2014
Springer
Subjects:
Medicine
Organic Chemistry
Pharmacology/Toxicology
Pharmacy
Pyrimidines
dicarboxylic acids
6-methyluracil
acute toxicity
antihypoxic activity
complexes
Online Access:Get full text
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Description
Summary:Water-soluble low-toxicity complexes of 6-methyluracil and its derivatives with succinic and fumaric acids were synthesized. The synthesized complexes were tested for antihypoxic activity.
ISSN:0091-150X
1573-9031
DOI:10.1007/s11094-014-1055-1