Effect of diuretics on plasma aldosterone and potassium in primary hypertension: A systematic review and meta‐analysis

Aim By contrast with drugs inhibiting the renin‐angiotensin‐aldosterone system (RAAS), diuretics stimulate renin release by the kidneys. Although plasma aldosterone (PA) is thought to be mainly regulated by RAAS activity, serum potassium has been shown to be an important factor in animal models and...

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Bibliographic Details
Published in:	British journal of clinical pharmacology Vol. 88; no. 5; pp. 1964 - 1977
Main Authors:	McNally, Ryan J., Farukh, Bushra, Chowienczyk, Philip J., Faconti, Luca
Format:	Journal Article
Language:	English
Published:	England 01-05-2022
Subjects:	aldosterone Aldosterone - pharmacology Aldosterone - therapeutic use Antihypertensive Agents - pharmacology Antihypertensive Agents - therapeutic use Blood Pressure Diuretics - pharmacology Diuretics - therapeutic use Humans hypertension Hypertension - drug therapy Potassium renin Thiazides - pharmacology Thiazides - therapeutic use blood pressure potassium hypertension aldosterone renin
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