Multimodality characteristics of multifocal choroid plexus carcinoma with bilateral calvarial defects in a dog

An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial de...

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Bibliographic Details
Published in:	Veterinary radiology & ultrasound Vol. 62; no. 3; pp. E20 - E25
Main Authors:	Hughes, Jonathan R., Taylor‐Brown, Frances E., Greville‐Heygate, Oliver, Constantino‐Casas, Fernando, Williams, David L., Genain, Marie‐Aude
Format:	Journal Article
Language:	English
Published:	England 01-05-2021
Subjects:	brain neoplasia calvarium skull defect brain neoplasia skull defect calvarium
Online Access:	Get full text
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Summary:	An 8‐year‐old male intact miniature poodle presented for blindness, obtundation, tetraparesis, and vestibular signs. Magnetic resonance imaging, radiography, and ultrasound revealed a left piriform lobe lesion, right cerebellar and left brainstem lesions, and hydrocephalus and bilateral calvarial defects. Histopathology confirmed a choroid plexus carcinoma with meningeal and intraventricular metastases. The calvarial defect did not show evidence of necrosis, osteoclastic resorption, inflammation or neoplastic infiltration, reflecting a quiescent calvarial atrophy or dysplasia. These novel findings supported inclusion of bone atrophy secondary to chronic increased intracranial pressure as a differential diagnosis for large calvarial defects in dogs with choroid plexus carcinoma.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1058-8183 1740-8261
DOI:	10.1111/vru.12732