Photodynamic therapy in fibrosarcoma BALB/c animal model: Observation of the rebound effect

•One-point fluorescence is employed to follow the photosensitizer during the photodynamic treatment of an animal model.•For certain tumor sites the "rebound effect" is observed: fluorescence signal increases 24h after illumination.•The “rebound effect” is used to perform a second illuminat...

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Bibliographic Details
Published in:	Photodiagnosis and photodynamic therapy Vol. 21; pp. 98 - 107
Main Authors:	Eugenia, Etcheverry María, Ángel, Pasquale Miguel, Anabella, Gutiérrez, Solange, Bibé, Carlos, Ponzinibbio, Horacio, Poteca, Mario, Garavaglia
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01-03-2018
Subjects:	Animals Disease Models, Animal Fibrosarcoma Fibrosarcoma - drug therapy Fluorescence spectra Mesoporphyrins - pharmacokinetics Mesoporphyrins - therapeutic use Mice Mice, Inbred BALB C Photochemotherapy - methods Photodynamic therapy Photosensitizer accumulation Photosensitizing Agents - pharmacokinetics Photosensitizing Agents - therapeutic use Fibrosarcoma Photodynamic therapy Photosensitizer accumulation Fluorescence spectra
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