Ghrelin Exerts Analgesic Effects through Modulation of IL-10 and TGF-β Levels in a Rat Model of Inflammatory Pain

Ghrelin is a peptide with attenuating effect on inflammatory pain. Both anti- and pro-inflammatory mediators have a role in the nociception and development of pain and hyperalgesia. IL-10 and TGF-β are anti-inflammatory cytokines and inhibit the expression of pro-inflammatory cytokines related to pe...

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Bibliographic Details
Published in:	Iranian biomedical journal Vol. 21; no. 2; pp. 114 - 119
Main Authors:	Azizzadeh, Faranak, Mahmoodi, Javad, Sadigh-Eteghad, Saeed, Farajdokht, Fereshteh, Mohaddes, Gisou
Format:	Journal Article
Language:	English
Published:	Iran Pasteur Institute 01-03-2017
Subjects:	Analgesics - pharmacology Animals Disease Models, Animal Full Length Ghrelin - pharmacology Inflammation - blood Inflammation - complications Interleukin-10 - blood Male Morphine - pharmacology Nociception - drug effects Pain - blood Pain - complications Rats, Wistar Transforming Growth Factor beta - blood TGF-β Pain Ghrelin IL-10 Formalin test
Online Access:	Get full text
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