Central nervous system lymphoma: primary lumbar nerve root infiltration

Primary malignant lymphoma of the central nervous system (CNS) is rare and only infrequently involves the spinal cord, usually in association with multifocal CNS spread. We report a case of primary lymphoma infiltrating lumbar nerve roots without evidence of systemic lymphoma. There has been an exce...

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Bibliographic Details
Published in:	Acta haematologica Vol. 81; no. 1; p. 44
Main Authors:	Toner, G C, Holmes, R, Sinclair, R A, Tang, S K, Schwarz, M A
Format:	Journal Article
Language:	English
Published:	Switzerland 1989
Subjects:	Ganglia, Spinal - pathology Humans Lumbosacral Region Lymphoma, Non-Hodgkin - drug therapy Lymphoma, Non-Hodgkin - pathology Lymphoma, Non-Hodgkin - radiotherapy Male Middle Aged Neoplasm Invasiveness Spinal Cord Neoplasms - drug therapy Spinal Cord Neoplasms - pathology Spinal Cord Neoplasms - radiotherapy
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Summary:	Primary malignant lymphoma of the central nervous system (CNS) is rare and only infrequently involves the spinal cord, usually in association with multifocal CNS spread. We report a case of primary lymphoma infiltrating lumbar nerve roots without evidence of systemic lymphoma. There has been an excellent response to combined modality therapy, comprising radiotherapy with intrathecal and intravenous cytotoxics. The patient remains well and active 22 months after diagnosis. The literature regarding these rare tumors is reviewed.
ISSN:	0001-5792
DOI:	10.1159/000205399