Fenretinide induces cytochrome c release, caspase 9 activation and apoptosis in the absence of mitochondrial membrane depolarisation

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Bibliographic Details
Published in:	Cell death and differentiation Vol. 10; no. 7; pp. 856 - 859
Main Authors:	Ulukaya, E, Pirianov, G, Kurt, M A, Wood, E J, Mehmet, H
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01-07-2003
Subjects:	Antineoplastic Agents - pharmacology Apoptosis Apoptosis - drug effects Apoptosis - physiology Caspase 9 Caspase Inhibitors Caspases - metabolism Cell death Cell Line, Tumor Cytochrome Cytochromes c - metabolism Enzyme Activation - drug effects Fenretinide - pharmacology Humans JNK Mitogen-Activated Protein Kinases Membrane Potentials - drug effects Membrane Potentials - physiology Metabolism Mitochondria Mitochondria - drug effects Mitochondria - metabolism Mitogen-Activated Protein Kinases - metabolism Receptors, Retinoic Acid - antagonists & inhibitors Receptors, Retinoic Acid - metabolism Signal Transduction - drug effects Signal Transduction - physiology
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Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1350-9047 1476-5403
DOI:	10.1038/sj.cdd.4401242