Frequency of the HFE C282Y and H63D polymorphisms in Brazilian malaria patients and blood donors from the Amazon region

Malaria is an endemic parasitosis and its causitive agent, Plasmodium, has a metabolism linked to iron supply. HFE is a gene with the polymorphisms C282Y and H63D, which are associated with a progressive iron accumulation in the organism leading to a disease called hereditary hemochromatosis. The ai...

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Bibliographic Details
Published in:	Genetics and molecular research Vol. 7; no. 1; pp. 60 - 64
Main Authors:	Torres, F R, Souza-Neiras, W C, D'Almeida Couto, A A, D'Almeida Couto, V S C, Cavasini, C E, Rossit, A R B, Machado, R L D, Bonini-Domingos, C R
Format:	Journal Article
Language:	English
Published:	Brazil 01-01-2008
Subjects:	Adult Alleles Animals Blood Donors Brazil - epidemiology Case-Control Studies Endemic Diseases Female Gene Frequency Heterozygote Humans Malaria - blood Malaria - epidemiology Malaria - genetics Malaria - parasitology Male Plasmodium Plasmodium falciparum - parasitology Plasmodium vivax - parasitology Polymorphism, Genetic Prevalence Brazil South America, Amazon R Brazil, Para
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