Synthesis, Antiaggregant, and Antioxidant Activity of 2-{[1-iso-butyl-3-methyl-7-(thietanyl-3)xanthin-8-yl]thio}acetic Acid Salts

8-Bromo-1- iso -butyl-3-methyl-7-(thietanyl-3)xanthine ( II ) was synthesized by alkylation of 8-bromo-3-methyl-7-(thietanyl-3)xanthine ( I ) with isobutyl bromide. Nucleophilic substitution of II with thioglycolic acid gave 2{[1- iso -butyl-3-methyl-7-(thietanyl-3)xanthin-8-yl]thio}acetic acid ( II...

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Bibliographic Details

Published in:	Pharmaceutical chemistry journal Vol. 54; no. 9; pp. 891 - 896
Main Authors:	Khaliullin, F. A., Mamatov, Zh. K., Timirkhanova, G. A., Samorodov, A. V., Bashirova, L. I.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01-12-2020 Springer
Subjects:	Acetic acid Antioxidants Aspirin Medicine Organic acids Organic Chemistry Pharmacology/Toxicology Pharmacy Search for New Drugs antiaggregant activity thietanes xanthines antioxidant activity
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