Estrogen attenuates progressive glomerular injury in hypercholesterolemic male Imai rats

Hypercholesterolemic Imai rats spontaneously develop proteinuria and glomerulosclerosis, especially in males. A sex difference in glomerular injury has been recognized, but the role of sex hormones in glomerular injury remains unclear. Therefore, we investigated whether estrogen administration influ...

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Bibliographic Details
Published in:	Nephron (2015) Vol. 69; no. 2; p. 159
Main Authors:	Sakemi, T, Toyoshima, H, Shouno, Y, Morito, F
Format:	Journal Article
Language:	English
Published:	Switzerland 1995
Subjects:	Analysis of Variance Animals Blood Pressure - drug effects Densitometry Estrogens - pharmacology Glomerulosclerosis, Focal Segmental - complications Glomerulosclerosis, Focal Segmental - metabolism Glomerulosclerosis, Focal Segmental - pathology Glomerulosclerosis, Focal Segmental - physiopathology Hypercholesterolemia - drug therapy Hypercholesterolemia - etiology Hypercholesterolemia - metabolism Kidney Glomerulus - drug effects Male Organ Size - drug effects Proteinuria - urine Rats Sex Characteristics
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