Hyskon induced pulmonary hemorrhage
Hyskon ®, a distension medium composed of dextran 70 in 10% dextrose in water, is often used during hysteroscopic procedures. Coagulopathy and pulmonary edema are the most commonly reported side effects encountered during its use. We present the first case report in which a healthy patient developed...
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| Published in: | Journal of clinical anesthesia Vol. 7; no. 4; pp. 323 - 325 |
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| Main Authors: | , , |
| Format: | Journal Article |
| Language: | English |
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United States
Elsevier Inc
01-06-1995
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| Abstract | Hyskon
®, a distension medium composed of dextran 70 in 10% dextrose in water, is often used during hysteroscopic procedures. Coagulopathy and pulmonary edema are the most commonly reported side effects encountered during its use. We present the first case report in which a healthy patient developed pulmonary hemorrhage from Hyskon
® use. The major side effects of Hyskon
® are discussed, as are the possible etiologies of the reported complication and the implications for anesthesiologists. |
|---|---|
| AbstractList | Hyskon, a distension medium composed of dextran 70 in 10% dextrose in water, is often used during hysteroscopic procedures. Coagulopathy and pulmonary edema are the most commonly reported side effects encountered during its use. We present the first case report in which a healthy patient developed pulmonary hemorrhage from Hyskon use. The major side effects of Hyskon are discussed, as are the possible etiologies of the reported complication and the implications for anesthesiologists. Hyskon ®, a distension medium composed of dextran 70 in 10% dextrose in water, is often used during hysteroscopic procedures. Coagulopathy and pulmonary edema are the most commonly reported side effects encountered during its use. We present the first case report in which a healthy patient developed pulmonary hemorrhage from Hyskon ® use. The major side effects of Hyskon ® are discussed, as are the possible etiologies of the reported complication and the implications for anesthesiologists. |
| Author | Romero, Robby M. Kreitzer, Joel M. Gabrielson, George V. |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/7546761$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1007/BF03008349 10.1097/00004311-198511000-00006 10.1016/S0015-0282(16)53962-4 10.1097/00006254-199104000-00002 10.1016/0049-3848(91)90009-L 10.1213/00000539-198905000-00024 10.1016/0952-8180(91)90228-F 10.1213/00000539-199108000-00012 10.1016/S0015-0282(16)48453-0 10.1001/archsurg.1967.01330110080011 10.7326/0003-4819-81-4-500 10.1213/00000539-199002000-00020 10.1016/S0015-0282(16)48942-9 10.1016/S0015-0282(16)59427-8 |
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| References | Atik (BIB10) 1967; 94 Mangar, Gerson, Baggish, Camporesi (BIB15) 1991; 73 Schinagl (BIB7) 1990; 70 Leake, Murphy, Zacur (BIB4) 1987; 48 Flordal, Svensson, Ljungstrom (BIB12) 1991; 62 Golan, Seidner, Bahar, Ron-El, Herman, Caspi (BIB5) 1990; 54 Ring (BIB14) 1985; 23 McLucas (BIB9) 1991; 46 Mangar, Gerson, Constantine, Lenzi (BIB2) 1989; 68 Lukacsko (BIB8) 1985; 44 Zbella, Moise, Carson (BIB3) 1985; 43 Data, Nies (BIB11) 1974; 81 Choban, Kalhan, Anderson, Collins (BIB6) 1991; 3 Borten, Seibert, Taymor (BIB13) 1983; 61 Mangar (BIB1) 1992; 39 Leake (10.1016/0952-8180(95)00035-G_BIB4) 1987; 48 Lukacsko (10.1016/0952-8180(95)00035-G_BIB8) 1985; 44 Data (10.1016/0952-8180(95)00035-G_BIB11) 1974; 81 Flordal (10.1016/0952-8180(95)00035-G_BIB12) 1991; 62 Mangar (10.1016/0952-8180(95)00035-G_BIB1) 1992; 39 Mangar (10.1016/0952-8180(95)00035-G_BIB2) 1989; 68 Mangar (10.1016/0952-8180(95)00035-G_BIB15) 1991; 73 Schinagl (10.1016/0952-8180(95)00035-G_BIB7) 1990; 70 Atik (10.1016/0952-8180(95)00035-G_BIB10) 1967; 94 McLucas (10.1016/0952-8180(95)00035-G_BIB9) 1991; 46 Zbella (10.1016/0952-8180(95)00035-G_BIB3) 1985; 43 Choban (10.1016/0952-8180(95)00035-G_BIB6) 1991; 3 Borten (10.1016/0952-8180(95)00035-G_BIB13) 1983; 61 Golan (10.1016/0952-8180(95)00035-G_BIB5) 1990; 54 Ring (10.1016/0952-8180(95)00035-G_BIB14) 1985; 23 |
| References_xml | – volume: 62 start-page: 355 year: 1991 end-page: 364 ident: BIB12 article-title: Effects of desmopressin and dextran on coagulation and fibrinolysis in healthy volunteers publication-title: Thromb Res contributor: fullname: Ljungstrom – volume: 48 start-page: 497 year: 1987 end-page: 499 ident: BIB4 article-title: Noncardiogenic pulmonary edema. a complication of operative hysteroscopy publication-title: Fertil Steril contributor: fullname: Zacur – volume: 46 start-page: 196 year: 1991 end-page: 200 ident: BIB9 article-title: Hyskon complications in hysteroscopic surgery publication-title: Obstet Gynecol Survey contributor: fullname: McLucas – volume: 81 start-page: 500 year: 1974 end-page: 504 ident: BIB11 article-title: Drugs five years later: dextran 40 publication-title: Ann Intern Med contributor: fullname: Nies – volume: 39 start-page: 975 year: 1992 end-page: 979 ident: BIB1 article-title: Anaesthetic implications of 32% Dextran-70 (Hyskon publication-title: Can J Anaesth contributor: fullname: Mangar – volume: 61 start-page: 755 year: 1983 end-page: 757 ident: BIB13 article-title: Recurrent anaphylactic reaction to intraperitoneal dextran 75 used for prevention of postsurgical adhesions publication-title: Obstet Gynecol contributor: fullname: Taymor – volume: 54 start-page: 939 year: 1990 end-page: 941 ident: BIB5 article-title: High-output left ventricular failure after dextran use in an operative hysteroscopy publication-title: Fertil Steril contributor: fullname: Caspi – volume: 73 start-page: 186 year: 1991 end-page: 189 ident: BIB15 article-title: Serum levels of Hyskon during hysteroscopic procedures publication-title: Anesth Analg contributor: fullname: Camporesi – volume: 43 start-page: 479 year: 1985 end-page: 480 ident: BIB3 article-title: Noncardiogenic pulmonary edema secondary to intrauterine instillation of 32% dextran 70 publication-title: Fertil Steril contributor: fullname: Carson – volume: 94 start-page: 664 year: 1967 end-page: 672 ident: BIB10 article-title: Dextran 40 and dextran 70. A review publication-title: Arch Surg contributor: fullname: Atik – volume: 23 start-page: 67 year: 1985 end-page: 95 ident: BIB14 article-title: Anaphylactoid reactions to plasma substitutes publication-title: Int Anesthesiol Clin contributor: fullname: Ring – volume: 68 start-page: 686 year: 1989 end-page: 687 ident: BIB2 article-title: Pulmonary edema and coagulopathy due to Hyskon publication-title: Anesth Analg contributor: fullname: Lenzi – volume: 70 start-page: 223 year: 1990 end-page: 224 ident: BIB7 article-title: Hyskon publication-title: Anesth Analg contributor: fullname: Schinagl – volume: 3 start-page: 317 year: 1991 end-page: 319 ident: BIB6 article-title: Pulmonary edema and coagulopathy following intrauterine instillation of 32% dextran-70 (Hyskon) publication-title: J Clin Anesth contributor: fullname: Collins – volume: 44 start-page: 560 year: 1985 end-page: 561 ident: BIB8 article-title: Noncardiogenic pulmonary edema secondary to intrauterine instillation of 32% dextran 70 [Letter] publication-title: Fertil Steril contributor: fullname: Lukacsko – volume: 39 start-page: 975 year: 1992 ident: 10.1016/0952-8180(95)00035-G_BIB1 article-title: Anaesthetic implications of 32% Dextran-70 (Hyskon®) during hysteroscopy. hysteroscopy syndrome publication-title: Can J Anaesth doi: 10.1007/BF03008349 contributor: fullname: Mangar – volume: 23 start-page: 67 year: 1985 ident: 10.1016/0952-8180(95)00035-G_BIB14 article-title: Anaphylactoid reactions to plasma substitutes publication-title: Int Anesthesiol Clin doi: 10.1097/00004311-198511000-00006 contributor: fullname: Ring – volume: 54 start-page: 939 year: 1990 ident: 10.1016/0952-8180(95)00035-G_BIB5 article-title: High-output left ventricular failure after dextran use in an operative hysteroscopy publication-title: Fertil Steril doi: 10.1016/S0015-0282(16)53962-4 contributor: fullname: Golan – volume: 46 start-page: 196 year: 1991 ident: 10.1016/0952-8180(95)00035-G_BIB9 article-title: Hyskon complications in hysteroscopic surgery publication-title: Obstet Gynecol Survey doi: 10.1097/00006254-199104000-00002 contributor: fullname: McLucas – volume: 62 start-page: 355 year: 1991 ident: 10.1016/0952-8180(95)00035-G_BIB12 article-title: Effects of desmopressin and dextran on coagulation and fibrinolysis in healthy volunteers publication-title: Thromb Res doi: 10.1016/0049-3848(91)90009-L contributor: fullname: Flordal – volume: 68 start-page: 686 year: 1989 ident: 10.1016/0952-8180(95)00035-G_BIB2 article-title: Pulmonary edema and coagulopathy due to Hyskon® (32% dextran-70) administration publication-title: Anesth Analg doi: 10.1213/00000539-198905000-00024 contributor: fullname: Mangar – volume: 3 start-page: 317 year: 1991 ident: 10.1016/0952-8180(95)00035-G_BIB6 article-title: Pulmonary edema and coagulopathy following intrauterine instillation of 32% dextran-70 (Hyskon) publication-title: J Clin Anesth doi: 10.1016/0952-8180(91)90228-F contributor: fullname: Choban – volume: 73 start-page: 186 year: 1991 ident: 10.1016/0952-8180(95)00035-G_BIB15 article-title: Serum levels of Hyskon during hysteroscopic procedures publication-title: Anesth Analg doi: 10.1213/00000539-199108000-00012 contributor: fullname: Mangar – volume: 43 start-page: 479 year: 1985 ident: 10.1016/0952-8180(95)00035-G_BIB3 article-title: Noncardiogenic pulmonary edema secondary to intrauterine instillation of 32% dextran 70 publication-title: Fertil Steril doi: 10.1016/S0015-0282(16)48453-0 contributor: fullname: Zbella – volume: 94 start-page: 664 year: 1967 ident: 10.1016/0952-8180(95)00035-G_BIB10 article-title: Dextran 40 and dextran 70. A review publication-title: Arch Surg doi: 10.1001/archsurg.1967.01330110080011 contributor: fullname: Atik – volume: 81 start-page: 500 year: 1974 ident: 10.1016/0952-8180(95)00035-G_BIB11 article-title: Drugs five years later: dextran 40 publication-title: Ann Intern Med doi: 10.7326/0003-4819-81-4-500 contributor: fullname: Data – volume: 70 start-page: 223 year: 1990 ident: 10.1016/0952-8180(95)00035-G_BIB7 article-title: Hyskon® (32% dextran 70), hysteroscopic surgery and pulmonary edema [Letter] publication-title: Anesth Analg doi: 10.1213/00000539-199002000-00020 contributor: fullname: Schinagl – volume: 44 start-page: 560 year: 1985 ident: 10.1016/0952-8180(95)00035-G_BIB8 article-title: Noncardiogenic pulmonary edema secondary to intrauterine instillation of 32% dextran 70 [Letter] publication-title: Fertil Steril doi: 10.1016/S0015-0282(16)48942-9 contributor: fullname: Lukacsko – volume: 48 start-page: 497 year: 1987 ident: 10.1016/0952-8180(95)00035-G_BIB4 article-title: Noncardiogenic pulmonary edema. a complication of operative hysteroscopy publication-title: Fertil Steril doi: 10.1016/S0015-0282(16)59427-8 contributor: fullname: Leake – volume: 61 start-page: 755 year: 1983 ident: 10.1016/0952-8180(95)00035-G_BIB13 article-title: Recurrent anaphylactic reaction to intraperitoneal dextran 75 used for prevention of postsurgical adhesions publication-title: Obstet Gynecol contributor: fullname: Borten |
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®, a distension medium composed of dextran 70 in 10% dextrose in water, is often used during hysteroscopic procedures. Coagulopathy and pulmonary edema... Hyskon, a distension medium composed of dextran 70 in 10% dextrose in water, is often used during hysteroscopic procedures. Coagulopathy and pulmonary edema... |
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| SubjectTerms | Anesthesia Blood Cell Count Coagulopathy dextran Dextrans - adverse effects Dilatation and Curettage Female hemoptysis Hemoptysis - chemically induced Humans Hysteroscopy Middle Aged Pulmonary Edema - chemically induced Pulmonary Edema - complications |
| Title | Hyskon induced pulmonary hemorrhage |
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