Synthesis of IL-2 mRNA in cells of rat hypothalamic structures after injection of short peptides

In situ hybridization on paraffin sections of the rat brain showed that synthetic peptides Vilon, Epithalon, and Cortagen modulated the expression of IL-2 gene in vivo in cells of some hypothalamic structures depending on the terms and routes of administration.

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Bibliographic Details
Published in:	Bulletin of experimental biology and medicine Vol. 139; no. 6; pp. 718 - 720
Main Authors:	Kazakova, T B, Barabanova, S V, Novikova, N S, Glushikhina, M S, Khavinson, V Kh, Malinin, V V, Korneva, E A
Format:	Journal Article
Language:	English
Published:	United States Springer Nature B.V 01-06-2005
Subjects:	Administration, Inhalation Animals Hypothalamus - cytology Hypothalamus - metabolism Immunohistochemistry In Situ Hybridization Injections, Intramuscular Interleukin-2 - biosynthesis Interleukin-2 - genetics Male Oligopeptides - administration & dosage Oligopeptides - chemistry Oligopeptides - pharmacology Rats Rats, Sprague-Dawley RNA, Messenger - biosynthesis RNA, Messenger - genetics
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Description
Summary:	In situ hybridization on paraffin sections of the rat brain showed that synthetic peptides Vilon, Epithalon, and Cortagen modulated the expression of IL-2 gene in vivo in cells of some hypothalamic structures depending on the terms and routes of administration.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-005-0388-x