Reduction of acute tubular necrosis (ATN) by furosemide and steroids in cadaveric kidney recovery

One hundred fifty human cadaver kidneys have been preserved by a combination of topical hypothermia and pulsatile perfusion with cryoprecipitated plasma in our laboratory. Post-transplant acute renal failure was reduced from 58 to 21 per cent in those kidneys protected with furosemide and methylpred...

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Bibliographic Details
Published in:	The American journal of surgery Vol. 129; no. 3; p. 246
Main Authors:	McCabe, R, Stevens, L E, Subramamian, A, Lattes, C, Hashim, G M
Format:	Journal Article
Language:	English
Published:	United States 01-03-1975
Subjects:	Acute Kidney Injury - prevention & control Adolescent Adult Aged Cadaver Child Child, Preschool Drug Evaluation Female Furosemide - pharmacology Humans Kidney Transplantation Kidney Tubular Necrosis, Acute - prevention & control Male Methylprednisolone - pharmacology Middle Aged Organ Preservation - methods Perfusion - methods Refrigeration Time Factors Tissue Donors Tissue Preservation - methods Transplantation, Homologous
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Summary:	One hundred fifty human cadaver kidneys have been preserved by a combination of topical hypothermia and pulsatile perfusion with cryoprecipitated plasma in our laboratory. Post-transplant acute renal failure was reduced from 58 to 21 per cent in those kidneys protected with furosemide and methylprednisolone.
ISSN:	0002-9610
DOI:	10.1016/0002-9610(75)90232-9