Anesthesia with antiphospholipid antibodies: Anesthetic management of a parturient with lupus anticoagulant and anticardiolipin antibody

Anesthesia with antiphospholipid antibodies: Anesthetic management of a parturient with lupus anticoagulant and anticardiolipin antibody

The anesthetic management of a parturient with a circulating lupus anticoagulant and an anticardiolipin antibody presenting to the obstetric suite taking heparin and aspirin is discussed. Issues concerning placement of a regional anesthetic with recent aspirin ingestion and heparin therapy are discu...

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Published in:Journal of clinical anesthesia Vol. 8; no. 1; pp. 49 - 53
Main Authors: Fahy, Brenda G., Malinow, Andrew M.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01-02-1996
Subjects:
Adult
Anesthesia
Anesthesia, epidural
Anesthesia, Obstetrical
Antibodies - immunology
anticardiolipin antibody
Anticoagulants - therapeutic use
Aspirin - therapeutic use
Cardiolipins - immunology
Female
Heparin - therapeutic use
Humans
lupus anticoagulant
Lupus Coagulation Inhibitor - immunology
Phospholipids - immunology
Platelet Aggregation Inhibitors - therapeutic use
Pregnancy
Pregnancy Complications - immunology
thrombosis
thrombosis
lupus anticoagulant
anticardiolipin antibody
Anesthesia, epidural
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Abstract The anesthetic management of a parturient with a circulating lupus anticoagulant and an anticardiolipin antibody presenting to the obstetric suite taking heparin and aspirin is discussed. Issues concerning placement of a regional anesthetic with recent aspirin ingestion and heparin therapy are discussed. Documentation of heparin dissipation via a whole blood heparin concentration assay before induction of regional anesthesia, including several laboratory tests that could be used in monitoring coagulation status in this patient population, is discussed in detail.
AbstractList The anesthetic management of a parturient with a circulating lupus anticoagulant and an anticardiolipin antibody presenting to the obstetric suite taking heparin and aspirin is discussed. Issues concerning placement of a regional anesthetic with recent aspirin ingestion and heparin therapy are discussed. Documentation of heparin dissipation via a whole blood heparin concentration assay before induction of regional anesthesia, including several laboratory tests that could be used in monitoring coagulation status in this patient population, is discussed in detail.
Author Fahy, Brenda G.
Malinow, Andrew M.
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/8695080$$D View this record in MEDLINE/PubMed
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CitedBy_id crossref_primary_10_1136_ejhpharm_2017_001255
crossref_primary_10_1213_XAA_0000000000001182
crossref_primary_10_4266_kjccm_2008_23_1_36
crossref_primary_10_1213_ane_0b013e3181994f88
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Keywords thrombosis
lupus anticoagulant
anticardiolipin antibody
Anesthesia, epidural
Language English
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Snippet The anesthetic management of a parturient with a circulating lupus anticoagulant and an anticardiolipin antibody presenting to the obstetric suite taking...
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StartPage 49
SubjectTerms Adult
Anesthesia
Anesthesia, epidural
Anesthesia, Obstetrical
Antibodies - immunology
anticardiolipin antibody
Anticoagulants - therapeutic use
Aspirin - therapeutic use
Cardiolipins - immunology
Female
Heparin - therapeutic use
Humans
lupus anticoagulant
Lupus Coagulation Inhibitor - immunology
Phospholipids - immunology
Platelet Aggregation Inhibitors - therapeutic use
Pregnancy
Pregnancy Complications - immunology
thrombosis
Title Anesthesia with antiphospholipid antibodies: Anesthetic management of a parturient with lupus anticoagulant and anticardiolipin antibody
URI https://dx.doi.org/10.1016/0952-8180(95)00175-1
https://www.ncbi.nlm.nih.gov/pubmed/8695080
https://search.proquest.com/docview/78056147
Volume 8
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