Studies on the insulinomimetic effects of benzylamine, exogenous substrate of semicarbazide-sensitive amine oxidase enzyme in streptozotocin induced diabetic rats

Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO) is believed to be a bifunctional membrane protein. It is localized extracellularly and preferentially oxidizes short chain primary amines to aldehydes, hydrogen peroxide and ammonia, but also functions as an adhesion molecule,...

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Bibliographic Details
Published in:	Journal of Neural Transmission Vol. 114; no. 6; pp. 851 - 855
Main Authors:	Soltész, Zs, Tábi, T, Halász, A S, Pálfi, M, Kocsis, E, Magyar, K, Tóth, M, Szökö, E
Format:	Journal Article
Language:	English
Published:	Austria Springer Nature B.V 01-06-2007
Subjects:	Amine Oxidase (Copper-Containing) - blood Amine Oxidase (Copper-Containing) - drug effects Animals Benzylamines - pharmacology Benzylamines - therapeutic use Blood Glucose - drug effects Blood Glucose - physiology Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Experimental - enzymology Diabetes Mellitus, Experimental - physiopathology Down-Regulation - drug effects Down-Regulation - physiology Drug Synergism Drug Therapy, Combination Glycated Hemoglobin A - drug effects Glycated Hemoglobin A - metabolism Glycation End Products, Advanced - blood Hypoglycemic Agents - pharmacology Hypoglycemic Agents - therapeutic use Insulin - agonists Insulin - metabolism Male Nitric Oxide - metabolism Rats Rats, Wistar Vanadates - pharmacology Vanadates - therapeutic use
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