Post-proline cleaving enzyme in human cerebrospinal fluid from control patients and parkinsonian patients

Post-proline cleaving enzyme in human cerebrospinal fluid from control patients and parkinsonian patients

PPCE activity was found in human CSF by using a HPLC-fluorescence method. PPCE activity in CSF from control patients without neurological diseases was 2.19 +/- 0.78 (mean +/- SD) pmole (hr)-1.(ml)-1. PPCE activity in CSF from patients with Parkinson's disease was significantly decreased while P...

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Bibliographic Details
Published in:Biochemical medicine and metabolic biology Vol. 38; no. 3; p. 387
Main Authors: Hagihara, M, Nagatsu, T
Format: Journal Article
Language:English
Published: United States 01-12-1987
Subjects:
Chromatography, High Pressure Liquid
Humans
Parkinson Disease - cerebrospinal fluid
Parkinson Disease - enzymology
Serine Endopeptidases - cerebrospinal fluid
Spectrometry, Fluorescence
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Description
Summary:PPCE activity was found in human CSF by using a HPLC-fluorescence method. PPCE activity in CSF from control patients without neurological diseases was 2.19 +/- 0.78 (mean +/- SD) pmole (hr)-1.(ml)-1. PPCE activity in CSF from patients with Parkinson's disease was significantly decreased while PPCE activity in serum did not change significantly.
ISSN:0885-4505
DOI:10.1016/0885-4505(87)90103-4