Folate pathway modulation in Rhipicephalus ticks in response to infection

Folate pathways components were demonstrated to be present in RNA‐sequencing data obtained from uninfected and pathogen‐infected Rhipicephalus ticks. Here, PCR and qPCR allowed the identification of folate‐related genes in Rhipicephalus spp. ticks and in the tick cell line IDE8. Genes coding for GTP...

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Bibliographic Details
Published in:	Transboundary and emerging diseases Vol. 67; no. S2; pp. 94 - 99
Main Authors:	Dias, Filipa, Couto, Joana, Ferrolho, Joana, Seron, Gustavo S., Bell‐Sakyi, Lesley, Antunes, Sandra, Domingos, Ana
Format:	Journal Article
Language:	English
Published:	Germany Hindawi Limited 01-07-2020
Subjects:	Animals Ehrlichia canis - genetics Female folate Folic acid Folic Acid - genetics Functional analysis Gene expression Gene Expression Regulation - physiology Gene sequencing Genes Genetic engineering GTP cyclohydrolase GTP Cyclohydrolase - genetics Infections Infections - veterinary Modulation Pathogens Phosphorus-Oxygen Lyases - genetics Protozoan Proteins - genetics Real-Time Polymerase Chain Reaction - veterinary Rhipicephalus Rhipicephalus - genetics Ribonucleic acid RNA RNA Interference RNA, Messenger - genetics RNA-mediated interference RNAi Statistical methods Thymidylate synthase Thymidylate Synthase - genetics tick cell line Ticks tick‐borne diseases vector‐pathogen interface Vitamin B RNAi folate vector-pathogen interface tick-borne diseases tick cell line
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